Food Protein-Induced Enterocolitis Syndrome (FPIES)
The Request for Applications is for $1 million to expand our understanding of the processes that underlie food protein-induced enterocolitis syndrome, or FPIES, or to advance the development of new, effective FPIES treatments and prevention strategies. The mechanisms of FPIES are distinct from more common food allergies mediated by IgE antibodies, which often trigger skin and respiratory symptoms like redness, hives, and wheezing. In contrast, FPIES is mediated by cells within the immune system rather than by IgE antibodies and is associated primarily with delayed gastrointestinal symptoms that can be severe and cause dehydration, metabolic derangement, and shock.
At present, FPIES is not well-understood, and there are many unmet research needs that impact those living with FPIES and those caring for FPIES patients. FARE’s $1 million Request for Applications seeks to address key knowledge gaps and ultimately drive innovations in patient care.
The FPIES Innovation Summit and Request for Applications is made possible by the generosity and leadership of an anonymous donor.
Both Requests for Applications will be overseen by FARE’s new Scientific Advisory Council (SAC), an esteemed forum of subject matter experts who are working at the leading edge of diverse disciplines. They will review recent progress and identify innovative approaches that can be applied to food allergy investigations to help guide FARE’s future investments in clinical and preclinical research.
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For more information on the Diagnostic Challenge or to apply for this grant, visit here.
For more information of the FPIES RFA or to apply for this grant, visit here.